The problem with bringing the Mass Effect universe into fruition on the big screen relies on a singular story-line. The games focus on a plethora of different character arcs, quest-lines, and big bad enemies to overcome, but for a feature film to work it would have to funnel all of the best ideas into a single cohesive plot. Reapers vs all life is a given plot point. But the Mass Effect universe is broad and full of stories. It;s a guessing game about the synopsis until we hear otherwise.