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According to The Wrap, they've figured out who the villain in Marc Webb's Untitled Spider-Man Reboot will be, as played by the recently-announced Rhys Ifans, and it's a villain that's been discussed to be in the fourth movie even back when Sam Raimi was still going to direct it... The Lizard!
In the previous trilogy, Dr. Curt Connors was played by actor Dylan Baker, who had originally assumed he would be returning for Raimi's fourth movie, saying that the Lizard would indeed be next, but when it was decided to reboot the franchise and Marc Webb was brought on board, it was thought that maybe those plans had changed.

Who knows if and when Sony Pictures will make their own announcement confirming this (or not) or we find out who leaked this information? (Andrew Garfield was in London for the premiere of his new film Never Let Me Go tonight, so maybe that's where it came from? The Wrap ain't sayin'.) Either way, as fans who have been waiting for nearly ten months to find out more about what will happen with this reboot, let us know what you think of this choice.
 
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Rhys Ifans (the naked Brit in Notting Hill) has been cast in the Spider-Man reboot, as the villain. But Columbia won't say what villain, so now it's your turn. Who do you think they've cast this scraggly dude as?
 
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Emma Stone (Gwen Stacy) and Andrew Garfield (Spiderman)
There seemed to be some confusion on the part of the interwebz about whether or not red-haired EMMA STONE would play red-haired MARY JANE WATSON or blond-haired GWEN STACY. Regardless of the hair, Stone has been slected to portray the role of GWEN STACY. And there seems to be a lot of importance attached to this casting so THRALL WORLD is led to believe that MJ might not figure as prominent in the SPIDER-MAN reboot as producers rewind and start anew the telling of the popular comic book hero.

EMMA STONE [ZOMBIELAND] has been cast as the female lead in the upcoming Spider-Man film film from Columbia Pictures and Marvel Studios, it was announced today by Amy Pascal, co-chairman of Sony Pictures Entertainment and Matt Tolmach, president of Columbia Pictures.

Stone has been tapped for the role of GWEN STACY opposite ANDREW GARFIELD [THE SOCIAL NETWORK, THE IMAGINARIUM OF DOCTOR PARNASSUS] as Peter Parker.

The film, to be directed by Marc Webb [(500) DAYS OF SUMMER] from a screenplay by James Vanderbilt and produced by Avi Arad and Laura Ziskin, will begin production in December and will be released in theaters nationwide in 3D on July 3, 2012.